| 货号:SYN-1028-M001 | 规格:1 mg | 目录价:¥1736 |
| 货号:SYN-1028-M005 | 规格:5 mg | 目录价:¥3024 |
| 货号:SYN-1028-M010 | 规格:10 mg | 目录价:¥4690 |
| 货号:SYN-1028-M050 | 规格:50 mg | 目录价:¥15806 |
| 货号:SYN-1028-M100 | 规格:100 mg | 目录价:¥询价 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CC-401 hydrochloride
别名:
CC401
产品描述:
CC-401 is a competitive inhibitor of the ATP binding site in the active, phosphorylated, form of JNK. This prevents JNK from phosphorylating its various target molecules, including the amino terminus of c-Jun. It is a potent inhibitor of all three forms of JNK (Ki of 25-50 nM), and has at least 40-fold selectivity for JNK compared with other related kinases, including: p38, ERK, IKK2, PKC, Lck, and ZAP70. CC-401 acts to inhibit JNK signaling by competitive binding to the adenosine triphosphate-binding site in the active, phosphorylated, form of JNK, resulting in inhibition of the phosphorylation of JNK targets, such as the amino-terminal activation domain of the transcription factor, c-Jun. In cell-based assays, 1-5 muM CC-401 provides specific JNK inhibition.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
388.4 . 36.5
产品形式:
solid
产地:
瑞士
纯度:
>95%
CAS号:
395104-30-0
分子式:
C22H24N6O . HCl
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