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折扣/货期| 货号：GTX53827 | 规格：100μg | 目录价：￥5000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CD11b antibody [OX-42] (Biotin)
别名:
Integrin Subunit Alpha M , Cd11B , Itgam
反应种属:
Rat
宿主来源:
Mouse
实验应用:
FCM, IHC, IHC-Fr
靶标/特异性:
Rat CD11b/c
同种型:
IgG2a
免疫原:
Rat peritoneal macrophages
克隆性:
Monoclonal
克隆号:
OX-42
纯化方式:
Protein G affinity purified
偶联:
Biotin
产品浓度:
0.1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, BSA, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement coated particles. It is identical to CR3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the RGD peptide in C3b. CD11b is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. The Mac1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, blood monocytes. CD11b is expressed on 8% spleen cells, 44% bone marrow cells and less than 1% of thymocytes and is commonly used as a microglial marker in nervous tissue.GTX53827 recognises CD11b expressed on most macrophages, including resident and activated peritoneal macrophages, Kupffer cells, around 35% of alveolar macrophages, dendritic cells, granulocytes and microglial cells in the brain.
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