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折扣/货期| 货号：GTX54075 | 规格：50μg | 目录价：￥8200 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IDO1 antibody [10.1]
别名:
indoleamine 2,3-dioxygenase 1 , IDO , IDO-1 , INDO
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
IHC-Fr, WB
靶标/特异性:
KO/KD validation is based on published data (PMID: 31681271).
同种型:
IgG3
免疫原:
Peptide corresponding to amino acids 78-184 of human IDO fused to GST.
克隆性:
Monoclonal
克隆号:
10.1
纯化方式:
Purified IgG
偶联:
Unconjugated
产品浓度:
1.0 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
45
产品形式:
Liquid
存储溶液:
PBS, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
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