官网链接
折扣/货期| 货号：GTX110602 | 规格：100μl | 目录价：￥4000 |
| 货号：GTX110602-S | 规格：25μl | 目录价：￥1700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CD31 antibody [N3C2], Internal
别名:
platelet and endothelial cell adhesion molecule 1 , CD31 , CD31/EndoCAM , GPIIA' , PECA1 , PECAM-1 , endoCAM
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-Fr, IHC-P, WB
同种型:
IgG
免疫原:
Recombinant protein encompassing a sequence within the Extracellular domain of human CD31. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
生产商:
GeneTex
功能与背景:
Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Isoform Delta15 is unable to protect against apoptosis. Modulates BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in human umbilical cord vein cells (HUVEC).
您可能感兴趣的产品
sPLA2 (human Type IIA) Polyclonal Antibody - Purified IgG
货号：45805
PAD3 Polyclonal Antibody
货号：33913
Growth Hormone (rat) Polyclonal Antibody for IHC
货号：C03904.25 µl
Goat Anti-ImmunoglobulinG (mouse) Polyclonal Antibody
货号：C03757.10 ml
Goat Anti-ImmunoglobulinG (rat) Polyclonal Antibody
货号：C03756.10 ml
Goat Anti-ImmunoglobulinG (guinea pig) Polyclonal Antibody
货号：C03755.10 ml
Sheep Anti-ImmunoglobulinG (guinea pig) Polyclonal Antibody
货号：C03754.10 ml
Horse Anti-ImmunoglobulinG (rabbit) Polyclonal Antibody
货号：C03753.5 ml
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询