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折扣/货期| 货号：11-496 | 规格：0.1 mg | 目录价：￥9038.25 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CD40 / TNFRSF5 Recombinant Protein
别名:
CD40,Bp50,CDW40,MGC9013,TNFRSF5,p50
实验应用:
ELISA,WB
表达系统:
HEK293 cells
保存温度:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
运输温度:
Blue Ice
产品形式:
Lyophilized
存储溶液:
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
产地:
美国
生产商:
Prosci
功能与背景:
CD40 is also known as TNFRSF5, Bp50, CDW40, MGC9013, TNFRSF5 and p50, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins, and plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. CD40 contains 4 cysteine-rich repeats in the extracellular domain, and is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines.
纯度:
>95% as determined by SDS-PAGE.
Accession #:
NP_001241.1
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