| 货号:96-850 | 规格:0.1 mg | 目录价:¥8687.25 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CD58 Recombinant Protein
别名:
CD58,LFA3,Ag3
实验应用:
ELISA,WB
表达系统:
HEK293 cells
保存温度:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
运输温度:
Blue Ice
产品形式:
Lyophilized
存储溶液:
Tris with Glycine, Arginine and NaCl, pH7.5
产地:
美国
生产商:
Prosci
功能与背景:
CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.
纯度:
>95% as determined by SDS-PAGE.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
生物活性:
Measured by its binding ability in a functional ELISA. Immobilized Human CD2, His Tag at 2 ug/mL (100 uL/well) can bind Human CD58, Fc Tag with a linear range of 10-156 ng/mL.
Accession #:
AAH05930
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