深圳欣博盛生物科技有限公司 a1

CD79 b Recombinant Protein
品牌:ProSci LLC
货号:96-156 规格:0.1 mg 目录价:¥9038.25
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CD79 b Recombinant Protein
别名:
CD79b, B29, IGB, Ig-beta
实验应用:
WB
表达系统:
HEK293 cells
保存温度:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
运输温度:
Blue Ice
产品形式:
Lyophilized
存储溶液:
Tris with Glycine, Arginine and NaCl, pH7.5
产地:
美国
生产商:
Prosci
功能与背景:
B-cell antigen receptor complex-associated protein beta chain (CD79b) is also known as B-cell-specific glycoprotein B29, Ig-beta,Immunoglobulin-associated B29 protein, B29 and IGB, which is a single-pass type I membrane protein containing one Ig-like V-type (immunoglobulin-like) domain and one ITAM domain.CD79b is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR).CD79b can enhance phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79b are the cause of agammaglobulinemia type 6 (AGM6) that is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development.
纯度:
>92% as determined by SDS-PAGE.
Accession #:
NP_000617
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