Soluble RANK Receptor Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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Soluble RANK Receptor Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：40-300-0.02 mg	规格：0.02 mg	目录价：￥3783
货号：40-300-0.1 mg	规格：0.1 mg	目录价：￥5674.5

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Soluble RANK Receptor Recombinant Protein

别名:

FEO, OFE, ODFR, OSTS, PDB2, RANK, CD265, OPTB7, TRANCER, LOH18CR1, Tumor necrosis factor receptor superfamily member 11A, Osteoclast differentiation factor receptor

表达系统:

E. coli

保存温度:

The lyophilized Soluble RANK Receptor recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Soluble RANK Receptor is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Soluble RANK Receptor recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

运输温度:

Blue Ice

产品形式:

Lyophilized

产地:

美国

生产商:

Prosci

功能与背景:

RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic-cell-membrane protein, which by interacting with RANKL augments the ability of dendritic cells to stimulate naïve T cell proliferation and to promote the survival of RANK + T cells. RANK is also expressed in a variety of tissues including skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. The RANK/RANKL interaction is important in the regulation of osteoclastogenesis and in dendritic-cell-mediated T cell immune responses. Impairments in RANK signaling have been implicated in the induction of expansile osteolysis and Paget disease of bone (PDB2). Recombinant human sRANK receptor is a 19.3 kDa polypeptide containing the TNFR homologous cysteine rich portion of the extracellular domain of RANK receptor (175 amino acid residues).

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

生物活性:

Biological activity was determined by its ability to suppress the production of IFN - gamma from human PBMCs.

Accession #:

NP_001257878.1

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