| 货号:GTX10540 | 规格:100μl | 目录价:¥4200 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Cyclin D1 antibody [DCS-6]
别名:
cyclin D1 , BCL1 , D11S287E , PRAD1 , U21B31
反应种属:
Human, Monkey, Mouse, Rat
宿主来源:
Mouse
实验应用:
ICC/IF, IHC-Fr, IHC-P, IP, WB
靶标/特异性:
Does not cross-react with other D-type cyclins.
同种型:
IgG2a
免疫原:
recombinant human Cyclin D1 protein.
克隆性:
Monoclonal
克隆号:
DCS-6
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
34
产品形式:
Liquid
存储溶液:
Ascites, 15mM Sodium azide.
生产商:
GeneTex
功能与背景:
During each cell cycle cyclins undergo periodic accumulation and destruction. As key regulators of the cell cycle the cyclins control important transitions by activating Cdks. Early in the G1 phase of the cell cycle cyclin D1 induction is followed by cyclin E induction. This sequential progression is marked early on in G1 by the activation of Cdk4 and in mid to late G1 by the activation of Cdk2 and the hyperphosphorylation of pRB. The final transition into S phase is thought to be dependent on the increased expression and association of cyclin E and Cdk2.
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