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折扣/货期| 货号：GTX10519 | 规格：100μl | 目录价：￥6400 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
FADD antibody [FD19]
别名:
Fas associated via death domain , GIG3 , MORT1
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, IP, WB
同种型:
IgG1
免疫原:
purified recombinant human FADD.
克隆性:
Monoclonal
克隆号:
FD19
纯化方式:
Purified immunoglobulin
偶联:
Unconjugated
产品浓度:
~2 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
23
产品形式:
Liquid
存储溶液:
PBS, 15mM Sodium azide.
生产商:
GeneTex
功能与背景:
FADD (Fas Associated Death Domain) is an apoptosis adapter molecule enabling transduction of the apoptosis signal initiated via the FasL/Fas receptor interaction. The protein contains a C-terminal death domain that interacts with the Fas receptor death domain. The N-terminus contains a death effectors domain (DED, which recruits caspase to the death inducing signaling complex (DISC) and initiates the apoptotic caspase cascade. FADD is implicated in non-apoptotic cellular pathways such as the regulation of cell cycle machinery in T lymphocytes. This is connected to the phosphorylation state of FADD and to the FasL/TRAIL-induced transcriptional activation of c-fos protooncogene. FADD also interacts with the hepatitis C virus core protein in the HEK-293 cell line.
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