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折扣/货期| 货号：AG-CN2-0028-M001 | 规格：1 mg | 目录价：￥300 |
| 货号：AG-CN2-0028-M005 | 规格：5 mg | 目录价：￥720 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Cyclopamine
别名:
11-Deoxyjervine; 11-Deoxojervine; HSDB 3505
产品描述:
Cell permeable steroidal alkaloid. Specific sonic hedgehog (Shh) signaling pathway inhibitor. Directly interacts/inhibits Smo (smoothened) [1-4]. Teratogenic [1] and antitumor compound. Inhibits tumor cell growth and progression. Shows selective activity against Shh-dependent tumors [5-11]. Blocks abnormal cell growth associated with oncogenic mutations of Ptch and Smo in fibroblasts [2]. Arrests cell cycle at G0/G1 [6]. Apoptosis inducer [8].
宿主来源:
Isolated from Veratrum californicum.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
411.6
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
产地:
瑞士
纯度:
>98%
CAS号:
4449-51-8
分子式:
C27H41NO2
溶解度:
Soluble in ethanol, methanol, DMF or DMSO. Insoluble in water.
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