Cyclosporin A-其他小分子化合物-深圳欣博盛生物科技有限公司

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Cyclosporin A

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CDX-C0365-M025	规格：25 mg	目录价：￥1134
货号：CDX-C0365-M100	规格：100 mg	目录价：￥3332

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Cyclosporin A

别名:

Antibiotic S 7481F1; Ciclosporin A; CsA; Cyclosporine; NSC 290193; Ramihyphin A

产品描述:

Cyclosporin A is a potent immunosuppressant. It forms a complex with cyclophilin D and inhibits the activity of the calcium/calmodulin-dependent protein phosphatase 2B (PP2B; calcineurin). Cyclosporin A prevents the dephosphorylation of nuclear factor of activated T cells (NFAT) transcription factor, leading to disruption of T cell activation and it suppresses proliferation of cytotoxic T cells and inhibits the production of T cell-derived mediators such as interleukin-2 (IL-2). Because of its powerful immunosuppressant activity, cyclosporin A has long been used for the prevention of transplant rejection. Cyclosporin A is an anti-inflammatory compound in the treatment of several inflammatory skin diseases (e.g. atopic dermatitis) and with potential anti-rheumatic activity (rheumatoid arthritis). Cyclosporin A has been described to have antibacterial, antifungal, antiparasitic, autophagic, antiapoptotic and anticancer activity. It inhibits the mitochondrial permeability transition pore (MPTP) from opening, thus inhibiting cytochrome c release.

宿主来源:

Microbial

保存温度:

+20°C

运输温度:

Ambient

预期分子量:

1202.61

产品形式:

solid

产地:

瑞士