D-erythro-Dihydrosphingosine [Sphinganine]-其他小分子化合物-深圳欣博盛生物科技有限公司

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D-erythro-Dihydrosphingosine [Sphinganine]

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CR1-3556-M005

规格：5 mg

目录价：￥480

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

D-erythro-Dihydrosphingosine [Sphinganine]

别名:

Sphinganine (d18:0); Dihydrosphingosine; (2S,3R)-2-Aminooctadecane-1,3-diol

产品描述:

The metabolite sphinganine activates the CD4+ regulatory T (Treg) cells, which accumulate in the tumor microenvironment (TME) and suppress the immune system. Sphinganine activates the Treg cells by physically interacting with the transcription factor c-Fos, and consequently increasing Treg cell proliferation. Sphinganine is a precursor of ceramide and sphingosine as well as a substrate of sphingosine kinases, which generate sphinganine-1-phosphate. Sphinganine is an inhibitor of protein kinase C and phospholipases A2 and D. Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins, as well as in some cancers. Sphinganine has been proposed to function as a c-Src kinase inhibitor in a drug-induced cancer cell model.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

301.5

产品形式:

solid

产地:

瑞士

纯度:

>95%