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折扣/货期| 货号：10-022 | 规格：50 mg | 目录价：￥5370 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Darunavir . ethanolate
别名:
TMC114; TMC41629; UIC-94017; HSDB 7788; Prezista
保存温度:
Short Term Storage: +4C. Long Term Storage: -20C. Handling Advice: Keep cool and dry. Use/Stability: Stable for at least 2 years after receipt when stored at -20C.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
Darunavir ethanolate is a highly potent HIV protease inhibitor (IC50=3-6nM, depending on laboratory HIV-1 strain), an antiretroviral medication used to treat and prevent HIV/AIDS. The ethanolate formulation has some stability advantages compared to the free base Darunavir (Prod. No. AG-CR1-3712). Darunavir ethanolate is a second generation HIV-1 protease inhibitor that inhibits replication of various laboratory strains and clinical isolates of HIV-1, including those resistant to first generation protease inhibitors. It inhibits cell-free diffusion and cell-to-cell spread of HIV-1 in Jurkat cell populations. Formulations containing darunavir have been used in combination therapy for the treatment of HIV. Shown in a SARS-CoV-2 protease structure model study to potentially bind and inhibit the papain like viral protease (PLVP) of SARS-CoV-2, responsible for COVID-19.
纯度:
greater than or equal to 98% (HPLC)
CAS号:
635728-49-3
分子式:
C27H37N3O7S . C2H5OH
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