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折扣/货期| 货号：CDX-D0195-M025 | 规格：25 mg | 目录价：￥3024 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Dioscin
别名:
Collettiside III; Polyphyllin III; CCRIS 4123
产品描述:
Dioscin is a natural steroid saponin originally isolated from plants used in herbal remedies. It has anticancer, anti-inflammatory, immunoregulatory, antioxidant, hyoplipidemic, antiviral, neuroprotective and antifungal activities. It inhibits proliferation, induces autophagy and oxygen-mediated apoptosis in cancer cells. It has been shown to inhibit colon tumor growth and tumor angiogenesis through regulating VEGFR2 and AKT/MAPK pathways. It inhibits adipogenesis through the AMPK/MAPK pathway. Dioscin showed protective effect against liver fibrosis by potently inhibiting ITGA5. Promotes proliferation of pancreatic beta cells via Wnt/beta-catenin signaling pathways. It has been shown inhibit the nuclear transport of NF-kappa and the expression of reactive oxygen species (ROS) and consequently the expression of inflammasome targets such as NLRP3. Potent inhibitor of Skp2, component of the ubiquitin/proteasome degradation pathway.
宿主来源:
Plant
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
869.04
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
>98% (NMR)
CAS号:
19057-60-4
分子式:
C45H72O16
溶解度:
Soluble in DMSO (10mg/ml), DMF (10mg/ml) or ethanol (5mg/ml).
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