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折扣/货期| 货号：CDX-D0371-M005 | 规格：5 mg | 目录价：￥546 |
| 货号：CDX-D0371-M025 | 规格：25 mg | 目录价：￥1596 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Docetaxel
别名:
Taxotere®; NSC 628503; RP 56976; N-debenzoyl-N-tert-butoxycarbonyl-10-deacetyltaxol
产品描述:
Anticancer agent. Semisynthetic analog of taxol (paclitaxel). Inhibits microtubule disassembly and inhibits cell replication. Binds to and stabilizes the beta−tubulin subunit of microtubules, preventing depolymerization of the mitotic spindle thus leading to cell cycle arrest at G2/M and apoptosis. This cytotoxic activity has been widely exploited in suppressing oncogenic proliferation. Displays potent and broad antineoplastic properties, used mainly for the treatment of breast, ovarian, and non-small cell lung cancer. Also inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and displays immunomodulatory and pro-inflammatory properties by inducing various mediators of the inflammatory response. Also studied for use as a radiation-sensitizing agent.
宿主来源:
Synthetic.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
807.88
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>97% (HPLC)
CAS号:
114977-28-5
分子式:
C43H53NO14
溶解度:
Soluble in DMSO or ethanol.
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