深圳欣博盛生物科技有限公司 a1

E2A/TCF3 Rabbit Recombinant Antibody
品牌:ProSci LLC
货号:82-798 规格:100 ul 目录价:¥8371.35
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
E2A/TCF3 Rabbit Recombinant Antibody
别名:
TCF3; AGM8; E2A; E47; ITF1; TCF-3; VDIR; bHLHb21; transcription factor 3; E2A/TCF3
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
WB, ELISA
同种型:
IgG
克隆性:
Monoclonal
纯化方式:
Affinity purification
偶联:
Unconjugated
产品浓度:
Batch dependent
保存温度:
Store at -20℃. Avoid freeze / thaw cycles.
运输温度:
Blue Ice
预期分子量:
75kDa/67-80kDa
产品形式:
Liquid
存储溶液:
Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
产地:
美国
生产商:
Prosci
功能与背景:
This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
Accession #:
P15923
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