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折扣/货期| 货号：CDX-E0316-M010 | 规格：10 mg | 目录价：￥12250 |
| 货号：CDX-E0316-M025 | 规格：25 mg | 目录价：￥24500 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Elobixibat
别名:
A3309; AZD 7806; AJG 533; (2R)-N-[2-[[3,3-Dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-1,1-dioxido-5-phenyl-1,5-benzothiazepin-8-yl]oxy]acetyl]-2-phenylglycylglycine
产品描述:
Elobixibat is an inhibitor of the sodium/bile acid and sulfated solute cotransporter (ASBT), also known as the ileal bile acid transporter (IBAT) which is selective for ASBT over the hepatic sodium/bile acid cotransporter. Oral administration of elobixibat reduces methionine- and choline-deficient diet-induced increases in serum bile acid levels and hepatic inflammation, fibrosis, and cytokine gene expression in a mouse model of non-alcoholic steatohepatitis (NASH). Elobixibat lowers LDL cholesterol, increases serum GLP-1, promotes colon motility, and has the potential to treat metabolic syndrome. Elobixibat can be used to study constipation, dyslipidemia, non-alcoholic hepatitis and liver tumors.
宿主来源:
Synthetic
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
695.89
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
439087-18-0
分子式:
C36H45N3O7S2
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