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折扣/货期| 货号：CDX-E0229-M050 | 规格：50 mg | 目录价：￥1246 |
| 货号：CDX-E0229-M200 | 规格：200 mg | 目录价：￥3724 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Entecavir monohydrate
别名:
Baraclude; BMS 200475; SQ 34,676; 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate
产品描述:
Entecavir is an oral antiviral drug used in the treatment of hepatitis B (HBV) infection. It is marketed under the trade name Baraclude (BMS). Entecavir is a potent deoxyguanosine nucleoside analog with antiviral activity selective for hepadnaviruses. In vitro, the active intracellular form of entecavir, entecavir triphosphate, demonstrates a higher binding affinity for HBV DNA polymerase than the natural guanosine triphosphate substrate and effectively inhibits HBV DNA replication at 3 stages in the replication pathway: priming, reverse transcription and DNA-dependent DNA synthesis. Can be also used as a reference compound.
宿主来源:
Synthetic
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
295.29
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at RT.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
209216-23-9
分子式:
C12H15N5O3 . H2O
溶解度:
Solube in DMSO (10mg/ml), DMF (10mg/ml) or methanol. Sparingly soluble in water.
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