Everolimus-其他小分子化合物-深圳欣博盛生物科技有限公司

首页产品中心其他小分子化合物

Everolimus

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CDX-E0074-M100	规格：100 mg	目录价：￥7196
货号：CDX-E0074-M250	规格：250 mg	目录价：￥13804

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Everolimus

别名:

42-O-(2-Hydroxyethyl)rapamycin; NVP-RAD001; RAD001; SDZRAD; Zortress; Afinitor; Certican; Votubia

产品描述:

Macrolide antibiotic, inhibiting bacterial protein synthesis. Potent immunosuppressant. Binds with high affinity to the FK506 binding protein-12 (FKBP-12) to generate an immunosuppressive complex that inhibits the activation of the mammalian target of rapamycin (mTOR). More selective for the mTORC1 protein complex, with little impact on the mTORC2 complex, compared to Rapamycin. Anticancer agent. Inhibition of mTOR reduces the activity of effectors downstream, which leads to a blockage in the progression of cells from G1 into S phase, and subsequently inducing cell growth arrest, apoptosis and autophagy, resulting in reduction of cell proliferation, angiogenesis and glucose uptake. Inhibits tumor proliferation in vitro and in vivo.

宿主来源:

Isolated from Streptomyces hygroscopicus.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

958.2

产品形式:

solid

产地:

瑞士