FEN1 antibody-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

FEN1 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX70184

规格：100μl

目录价：￥4300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

FEN1 antibody

别名:

flap structure-specific endonuclease 1 , FEN-1 , MF1 , RAD2

反应种属:

Human

宿主来源:

Mouse

实验应用:

同种型:

IgG

免疫原:

Recombinant full-length human FEN-1 protein.

克隆性:

Polyclonal

克隆号:

纯化方式:

Unpurified

偶联:

Unconjugated

产品浓度:

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, no preservatives.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. [provided by RefSeq, Jul 2008]

您可能感兴趣的产品

Tafazzin Polyclonal Antibody

SARS-CoV-2 (COVID-19) nsp3 antibody

货号：GTX135589-S

SARS-CoV-2 (COVID-19) nsp12 antibody

货号：GTX135467-S

SARS-CoV-2 (COVID-19) Nucleocapsid antibody