UBE3A antibody-多抗-深圳欣博盛生物科技有限公司

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UBE3A antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX70169

规格：50μl

目录价：￥4300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

UBE3A antibody

别名:

ubiquitin protein ligase E3A , ANCR , AS , E6-AP , EPVE6AP , HPVE6A

反应种属:

Human

宿主来源:

Rabbit

实验应用:

IHC, WB

同种型:

IgG

免疫原:

Recombinant protein encoding amino acids residues 1-851 of human UBE3A expressed in E. coli.

克隆性:

Polyclonal

克隆号:

纯化方式:

Rabbit Polyclonal Antiserum

偶联:

Unconjugated

产品浓度:

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

Unpurified Serum, no preservatives.

生产商:

GeneTex

功能与背景:

This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]

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