Flt-3 / Flk-2 Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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Flt-3 / Flk-2 Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：11-284

规格：0.1 mg

目录价：￥10126.35

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Flt-3 / Flk-2 Recombinant Protein

别名:

Flt-3,Flk-2,STK-1,CD135,FLK2,FLT-3

实验应用:

表达系统:

HEK293 cells

保存温度:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

PBS, pH7.4

产地:

美国

生产商:

Prosci

功能与背景:

Flt-3(Receptor-type tyrosine-protein kinase FLT3) is also known as FLK-2(Fetal liver kinase-2), STK-1(Stem cell tyrosine kinase 1), CD135. FLT3 is a cytokine receptor which belongs to the receptor tyrosine kinase class III. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.

纯度:

>90% as determined by SDS-PAGE.

Accession #:

NP_034359.2

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