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折扣/货期| 货号：CDX-F0339-M050 | 规格：50 mg | 目录价：￥490 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Formononetin
别名:
Biochanin B; NSC 93360; 7-Hydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one; 7-Hydroxy-3-(4-methoxyphenyl)chromone, 7-Hydroxy-4'-methoxyisoflavone
产品描述:
Formononetin is an isoflavonoid phytoestrogenic compound found in soy-based foods and is the precursor of daidzein. It acts as an agonist of the aryl hydrocarbon receptor and a selective inhibitor of ADH gamma (the gamma-isoform of alcohol dehydrogenase). It displays potent antitumor, antiviral, anti-inflammatory (inhibits NLRP3 inflammasome), antioxidant, neuroprotective and neuroinflammatory properties. Also shown to have vasorelaxant, antihypertensive and antihyperglycemic (AMPK activator) properties. Induces cell cycle arrest and apoptosis in several cancer cells in vitro and in vivo and shows anti-angiogenic (FGFR2 inhibitor), anti-invasive and anti-migratory effects. Increases adipocyte thermogenesis by modulating PPARgamma activity. Shown to promote early fracture healing through stimulating angiogenesis by up-regulating VEGFR-2/Flk-1 and endothelial repair and wound healing in a process involving the over-expression of Egr-1 transcription factor through the regulation of the ERK1/2 and p38 MAPK pathways. Binding to human cell-surface receptor HSPA5 and prevents SARS-CoV-2 spike protein from binding to HSPA5 SBDbeta in silico.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
268.26
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
485-72-3
分子式:
C16H12O4
溶解度:
Soluble in DMSO (30mg/ml), DMF (30mg/ml) or ethanol (1mg/ml).
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