FSCN1 Antibody / Fascin 1-单抗-深圳欣博盛生物科技有限公司

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FSCN1 Antibody / Fascin 1

品牌：NSJ Bio

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说明书

折扣/货期

货号：V4051SAF-100UG

规格：100 ug

目录价：￥6414.1

产品详情

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产品名称:

FSCN1 Antibody / Fascin 1

产品描述:

Recognizes a protein of 55kDa, which is identified as fascin-1. Its actin binding ability is regulated by phosphorylation. Antibody to fascin-1 is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkin s disease. It is uniformly negative in lymphoid cells, plasma cells, and myeloid cells. Fascin-1 is also expressed in dendritic cells. This marker may be helpful to distinguish between Hodgkin lymphoma and non-Hodgkin lymphoma in difficult cases. Also, the lack of expression of fascin-1 in the neoplastic follicles in follicular lymphoma may be helpful in distinguishing these lymphomas from reactive follicular hyperplasia in which the number of follicular dendritic cells is normal or increased. Antibody to fascin-1 has been suggested as a prognostic marker in neuroendocrine neoplasms of the lung as well as in ovarian cancer. Fascin-1 expression may be induced by Epstein-Barr virus (EBV) infection of B cells with the possibility that viral induction of fascin in lymphoid or other cell types must also be considered in EBV-positive cases.

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P

同种型:

Mouse IgG2a, kappa

免疫原:

A portion of amino acids 350-400 from the human FSCN1 protein was used as the immunogen for the FSCN1 antibody.

克隆性:

Monoclonal (mouse origin)