Recombinant STAT6 Antibody-单抗-深圳欣博盛生物科技有限公司

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Recombinant STAT6 Antibody

品牌：NSJ Bio

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说明书

折扣/货期

货号：V4052-100UG	规格：100 ug	目录价：￥6414.1
货号：V4052-20UG	规格：20 ug	目录价：￥2963.1

产品详情

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产品名称:

Recombinant STAT6 Antibody

产品描述:

STAT6 is a transcription factor in the Jak/STAT signal transduction pathway responsible for mediating IL-4 immune signaling. STAT6 was recently suggested to be a reliable marker to distinguish solitary fibrous tumors from other soft tissue neoplasms. Gene fusions are common in solitary fibrous tumors. Recent next generation sequencing studies demonstrated the presence of a NAB2-STAT6 fusion, formed by an intrachromosomal inversion fusing two neighboring genes on chromosome 12q13, in 55-100% of solitary fibrous tumors, regardless of tumor morphology or anatomical site. By immunohistochemistry, nuclear STAT6 expression can discriminate solitary fibrous tumors from its morphological mimics in the meninges, including meningioma, glioblastoma, gliosarcoma, haemangioblastoma, schwannoma and haemangioma. A recent study by Cheah, et al. using the rabbit monoclonal STAT6 antibody (Clone YE361) observed expression in all solitary fibrous tumors (54/54) tested, regardless of histology, anatomical site or CD34 status. Morphological mimics of solitary fibrous tumors were negative, demonstrating 100% specificity.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

IHC-P

同种型:

Rabbit IgG, kappa

免疫原:

Recombinant full-length human protein was used as the immunogen for the recombinant STAT6 antibody.

克隆性:

Recombinant Rabbit Monoclonal