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折扣/货期| 货号：AG-CN2-0529-M001 | 规格：1 mg | 目录价：￥600 |
| 货号：AG-CN2-0529-M005 | 规格：5 mg | 目录价：￥1800 |
| 货号：AG-CN2-0529-M025 | 规格：25 mg | 目录价：￥4560 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Fumagillin
别名:
Amebacilin; Fugilin; Fumidil; Fumadil B; NSC9168; U5762
产品描述:
Meroterpenoid antibiotic. Anticancer, antimicrobial, antimalarial and amoebicidal compound. Potent, selective and covalent inhibitor of methionine aminopeptidase-2 (MetAP2). Anti-angiogenic by impairing the growth of endothelial cells and altering gene expression. Inhibits endothelial cell proliferation in vitro and tumor-induced angiogenesis in vivo. Suppresses the HIV-1 infection of human macrophages through the inhibition of HIV-1 viral protein R (Vpr) activity. Inhibits neovascularization and might be useful in non-tumor diseases such as diabetic retinopathy, arthritis and psoriasis, which involve neovascularisation processes. Reduces diet-induced adipose tissue formation in mice, independent of its effects on angiogenesis.
宿主来源:
Isolated from Aspergillus fumigatus.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
458.6
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
产地:
瑞士
纯度:
>98% (1H-NMR)
CAS号:
23110-15-8
分子式:
C26H34O7
溶解度:
Soluble in DMSO, acetone or chloroform. Slightly soluble in methanol (5mg/ml) or ethanol. Insoluble in water.
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