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折扣/货期| 货号：40-591-0.005 mg | 规格：0.005 mg | 目录价：￥3783 |
| 货号：40-591-0.025 mg | 规格：0.025 mg | 目录价：￥5674.5 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
GASP-1 Recombinant Protein
别名:
GASP, GASP1, GASP-1, GASP, KIAA0443, G-protein coupled receptor-associated sorting protein 1
表达系统:
CHO cells
保存温度:
The lyophilized GASP-1 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted GASP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing GASP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted inhibitory TGF-β binding protein that contains multiple protease inhibitor structural domains. It is expressed primarily in the ovary, testis, and brain, and can act as a potent soluble inhibitor of myostatin and GDF-11, but not Activin-A. The GASP-1 gene encodes a 571 amino acid protein that contains a 29 amino acid secretion signal sequence, and multiple identifiable structural features, including a WAP domain, a follistatin/Kazal domain, an immunoglobulin domain, two tandem Kunitz domains, and a netrin domain. Recombinant human GASP-1 is a 542 amino acid protein that migrates at an apparent molecular weight of approximately 55-66 kDa by SDS-PAGE analysis under non-reducing conditions.
纯度:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
生物活性:
Determined by its ability to inhibit human Myostatin (GDF-8) activity in MCP-11 cells. The ED50 for this effect is 0.0025-0.0040 μg/mL in the presence of 5 ng/mL of human Myostatin (GDF-8).
Accession #:
NP_001092880.1
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