深圳欣博盛生物科技有限公司 a1

GDF-2 Recombinant Protein
品牌:ProSci LLC
货号:11-145 规格:0.05 mg 目录价:¥14303.25
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GDF-2 Recombinant Protein
别名:
GDF-2,GDF2,BMP-9,BMP9
实验应用:
ELISA,WB
表达系统:
HEK293 cells
保存温度:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
运输温度:
Blue Ice
产品形式:
Lyophilized
存储溶液:
ACN, TFA in Water
产地:
美国
生产商:
Prosci
功能与背景:
Human Growth and differentiation factor 2 (GDF-2), also known as Bone morphogenetic protein 9 (BMP-9), is a member of the BMP subgroup of the TGF-beta superfamily proteins that signal through heterodimeric complexes composed of type I and type II BMP receptors. GDF-2 Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. ALK1 is a signalling receptor for bone morphogenetic protein-9 (BMP-9) in endothelial cells (ECs). BMP-9 bound with high affinity to ALK1 and endoglin, and weakly to the type-I receptor ALK2 and to the BMP type-II receptor (BMPR-II) and activin type-II receptor (ActR-II) in transfected COS cells. Binding of BMP-9 to ALK2 was greatly facilitated when BMPR-II or ActR-II were co-expressed.
纯度:
>95% as determined by SDS-PAGE.
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