| 货号:CDX-G0210-M025 | 规格:25 mg | 目录价:¥1064 |
| 货号:CDX-G0210-M100 | 规格:100 mg | 目录价:¥3192 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Genistein
别名:
CI-75610; NSC 36586; Baichanin A; Differenol A; 4',5,7-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
产品描述:
Genistein is an isoflavonoid phytoestrogen that has been found in soybeans and has kinase inhibitory, anticancer, pro-cancer and hepatoprotective properties. It is a cell-permeable, reversible, substrate competitive tyrosine kinase inhibitor (including EGFR phosphorylation), implicated in almost all cell growth and proliferation signal cascades. Genistein inhibits proliferation and induces cell cycle arrest and apoptosis in a variety of cancer cells. It is antiangiogenic agent, down-regulates the transcription of genes involved in controlling angiogenesis. On a molecular level it also inhibits mammalian DNA topoisomerase II and DNA methyltransferase, and binds to estrogen receptor beta. Genistein has also antidiabetic, anti-inflammatory, antimicrobial and antioxidant properties. It is an alpha-glucosidase inhibitor, PPAR activator, GLUT4-mediated glucose uptake inhibitor, MALT1 inhibitor and acts as an agonist at the GPR30 receptor.
宿主来源:
Plant
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
270.24
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
446-72-0
分子式:
C15H10O5
溶解度:
Soluble in DMSO (30mg/ml). Slightly soluble in ethanol. Insoluble in water.
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