| 货号:CDX-G0220-M005 | 规格:5 mg | 目录价:¥364 |
| 货号:CDX-G0220-M025 | 规格:25 mg | 目录价:¥1106 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Ginsenoside Rg3
别名:
20(S)-Ginsenoside-Rg3; Rg3; (3beta,12beta)-12,20-Dihydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
产品描述:
Ginsenoside Rg3 is a panaxadiol found in white and red P. ginseng. Show a broad range of biological in vitro and in vivo effects, including anticancer, antidiabetic, neuroprotective, antioxidant, anti-hypertensive, and anti-inflammatory actions. The anticancer mechanisms include induction of apoptosis and autophagy, inhibition of proliferation, inhibition of metastasis and angiogenesis, cell cycle arrest, immunomodulatory effects, sensitization to radiation, reducing multidrug resistance and inducing genotoxicity to the cancer cells. Ginsenoside Rg3 has been shown to inhibit the 5-HT3A and alpha3beta4 nACh receptors, the voltage-dependent Ca2+, K+, and Na+ channel currents. It is a scavenger of hydroxyl radicals and downregulated the expression of DNA methyltransferases, reducing global DNA methylation, modifying the methylation of the promoter region of some relevant genes in cancer. It enhances glucose-stimulated insulin secretion and activates AMPK. Ginsenoside Rg3 regulates NF-kappaB activity and suppresses the NLRP3 inflammasome activation through inhibition of its assembly.
宿主来源:
Plant
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
785.01
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
14197-60-5
分子式:
C42H72O13
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