货号:SYN-1158-M001 | 规格:1 mg | 目录价:¥2870 |
货号:SYN-1158-M005 | 规格:5 mg | 目录价:¥4844 |
货号:SYN-1158-M010 | 规格:10 mg | 目录价:¥6958 |
货号:SYN-1158-M050 | 规格:50 mg | 目录价:¥询价 |
货号:SYN-1158-M100 | 规格:100 mg | 目录价:¥询价 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GLPG0634
别名:
GLPG-0634; Filgotinib
产品描述:
GLPG0634 is a novel and specific inhibitor of JAK1 and JAK2 with IC(50) of 10nM and 28nM respectively measured by in vitro kinase assays (ATP 2µM). In particular GLPG0634, while being a potent inhibitor of JAK1 and JAK2 does not inhibit TYK2 or JAK3, and GLPG0634 exhibits a dramatically improved in vivo potency over structurally similar compounds. May be used for the prevention of variety of conditions in animals including inflammatory conditions, autoimmune diseases, proliferative diseases, transplant rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformation and/or diseases associated with hypersecretion of IL-6.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
425.5
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>95%
CAS号:
1206161-97-8
分子式:
C21H23N5O3S
溶解度:
Soluble in DMSO.
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