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折扣/货期| 货号：CDX-G0215-G025 | 规格：25 g | 目录价：￥980 |
| 货号：CDX-G0215-G100 | 规格：100 g | 目录价：￥3556 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Glycyrrhizic acid ammonium salt
别名:
Glycyrrhizin; 3-O-(2-O-beta-D-Glucopyranuronosyl-alpha-D-glucopyranuronosyl)-18beta-glycyrrhetinic acid ammonium salt; Monoammonium glycyrrhizinate; NSC 2800; NSC 35348
产品描述:
Glycyrrhizic acid is a natural triterpenoid saponin. It is an agonist of the human sweet taste receptor and is used as a flavorant. Glycyrrhizic acid has diverse biological activities, including antioxidant, anti-inflammatory, antidiabetic, anticancer, antimicrobial, hepatoprotective, neuroprotective and antiviral actions. Glycyrrhizic acid has been shown to be a 11-beta-hydroxysteroid dehydrogenase inhibitor, a functional inhibitor of HMGB1 and a highly selective and competitive inhibitor of kynurenine aminotransferase 2 (KAT2). It can enhance GLP-1 secretion through TGR5 activation and has an anti-inflammatory effect by attenuating the generation of excessive NO, PGE(2), and ROS and by suppressing the expression of pro-inflammatory genes through the inhibition of NF-kappa and PI3K activity. It has anti-angiogenic and apoptosis inducing properties. In addition, due to its amphiphilic nature glycyrrhizic acid is able to form self-associates in aqueous and non-aqueous media, as well as water soluble complexes with a wide range of lipophilic drugs. It has been identified as promising carrier material for anticancer therapy, due to its anti-cancer-related pharmacological activities, such as broad-spectrum anti-cancer ability, resistance to the tissue toxicity caused by chemotherapy and radiation, drug absorption enhancing effects and anti-multidrug resistance (MDR) mechanisms.
宿主来源:
Plant
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
839.96
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
>98% (Titr.)
CAS号:
53956-04-0
分子式:
C42H62O16 . NH3
溶解度:
Soluble in DMSO (10mg/ml). Slightly soluble in water (1mg/ml).
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