深圳欣博盛生物科技有限公司 a1

GSK-J1
货号:SYN-3030-M001 规格:1 mg 目录价:¥910
货号:SYN-3030-M005 规格:5 mg 目录价:¥1358
货号:SYN-3030-M010 规格:10 mg 目录价:¥2268
货号:SYN-3030-M050 规格:50 mg 目录价:¥8316
货号:SYN-3030-M100 规格:100 mg 目录价:¥询价
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GSK-J1
别名:
N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-beta-alanine
产品描述:
GSK-J1 is a potent inhibitor of the H3K27 histone demethylases JMJD3 (KDM6B) and UTX (KDM6A), with IC50 values of 28nM and 53nM, respectively. GSK-J1 also has less potent inhibitory activity against KDM5B, KDM5C and KDM5A, with IC50 values of 170, 550 and 6,800nM, respectively. It shows no activity against other histone demethylases (IC50 >20µM), and displays no significant inhibitory activity against 100 protein kinases at a concentration of 30µM.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
389.5
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>95%
CAS号:
1373422-53-7
分子式:
C22H23N5O2
溶解度:
Soluble in DMSO.
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