货号:CDX-H0299-M050 | 规格:50 mg | 目录价:¥1246 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Hederacoside C
别名:
Hederasaponin C; Kalopanaxsaponin B
产品描述:
Hederacoside C is a major bioactive constituent isolated from Hedera helix L. It exhibits biological properties such as antibacterial, expectorant, bronchodilator, bronchospasmolytic and anti-inflammatroy effects. It is widely used in the treatment of respiratory disorders involving acute respiratory infections, chronic inflammatory bronchitis and productive coughs. It reduces TNF-alpha, IL-1beta, IL-6, COX-2, and nitric oxide synthase (NOS) levels in a concentration-dependent manner and IL-1 receptor-associated kinase-1 (IRAK1) activity. It reduces scopolamine-induced memory impairment. Hederacoside C markedly suppressed TLR2 and TLR4 expressions by attenuating the MAPKs (p38, ERK, JNK) and NF-kappa (p65 and IkappaBalpha) pathways followed by decreasing the phosphorylation of p38, ERK, JNK, p65, and IkappaBalpha.
宿主来源:
Plant
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
1221.38
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
14216-03-6
分子式:
C59H96O26
溶解度:
Soluble in DMSO (5mg/ml), DMF (15mg/ml) or ethanol (10mg/ml).
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