官网链接
折扣/货期| 货号：AG-CN2-0118-C250 | 规格：250 ug | 目录价：￥1500 |
| 货号：AG-CN2-0118-M001 | 规格：1 mg | 目录价：￥4500 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Heptelidic acid
别名:
Koningic acid; Avocettin; FO-4443; BRN 5091359; HPA
产品描述:
Antibiotic [1, 2]. Potent selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GAPDH [3-7, 10, 11]. Anticancer compound [8]. Selectively kills high-glycolytic cancer cells through glucose-dependent active ATP deprivation [12]. Antimalarial [9]. Apoptosis inhibitor. DNA fragmentation and caspase-3 activation inhibitor [13,16]. Selective and competitive inhibitor of mammalian DNA polymerases beta, lambda and terminal deoxynucleotidyl transferase (TdT) in family X of pols [14]. Reduces lactate secretion and causes reductions in overall protein synthesis and production of IFN-alpha and TNF.
宿主来源:
Isolated from Trichoderma sp.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
280.3
产品形式:
solid
产地:
瑞士
纯度:
>95% (HPLC)
CAS号:
57710-57-3
分子式:
C15H20O5
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