| 货号:10-421 | 规格:0.1 mg | 目录价:¥10126.35 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Human ACE2 Recombinant Protein
别名:
ACE-related carboxypeptidase
Angiotensin-converting enzyme homolog
Metalloprotease MPROT15
表达系统:
Mammalian Cells
保存温度:
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚C for one week. Store at -20 to -80 ˚C for twelve months from the date of receipt.
运输温度:
Blue Ice
产品形式:
Lyophilized
存储溶液:
Supplied as lyophilized from PBS, pH 7.5. Please reconstitute the protein with ddH2O to the concentration with 1mg/ml.
产地:
美国
生产商:
Prosci
功能与背景:
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
纯度:
>90% as determined by SDS-PAGE quantitative densitometry by Coomassie Blue Staining.
Accession #:
NP_001358344.1 or Q9BYF1
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