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折扣/货期| 货号：SIH-400-50MG | 规格：50 mg | 目录价：￥4867.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Hydroxychloroquine
别名:
Hydroxychloroquine sulphate, 7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline
产品描述:
Autophagy inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
433.95
产品形式:
White to off-white powder.
产地:
加拿大
功能与背景:
Hydroxychloroquine was first established as an anti-malarial agent, but is now being used in a variety of applications, including the inhibition of autopagy. Hydroxychloroquine is a lysosomotropic agent and therefore inhibits autophagy by obstructing the final step of autophagy, the fusion of autophagosomes with lysosomes, thereby preventing the acidification of the lysosomal compartment. In the context of cancer, autophagy is thought to be adopted by tumor cells to survive in the nutrient-deficient and hypoxic tumor environment. Hydroxychloroquine has therefore been studied extensively within the context of certain cancers.
纯度:
≥98%
来源:
Synthetic
CAS号:
747-36-4
分子式:
C18H26ClN3O•H2SO4
溶解度:
Soluble in greater than 20 mg/ml H2O.
PubChem CID:
12947
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