货号:CDX-I0172-M100 | 规格:100 mg | 目录价:¥1064 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Icariin
别名:
4'-O-Methyl-8-gamma,gamma-dimethylallylkaempferol-3-rhamnoside-7-glucoside; Leariline
产品描述:
Icariin, the active component of the Chinese medicinal plant E. brevicornum. It has been shown to have anti-inflammatory, anticancer, antioxidant, osteoprotective, neuroprotective and cardioprotective activity. It has been shown to enhance bone formation and bone regeneration. Icariin may be beneficial to Alzheimer's disease by reducing the production of extracellular amyloid plaques and intracellular neurofibrillary tangles and inhibiting phosphodiesterase-5 activity. The anti-cancer activity is related to various mechanisms such as apoptosis and autophagy induction, cell cycle modulation, antiangiogenesis and antimetastasis, modulating multidrug resistance and immunomodulation. Icariin interacts with several pathways, like PDE, TGF-beta, MAPK, PPAR, NOS, IGF, Sirtuin and others. Icariin has been shown to inhibit the NF-kappa activation pathway and NLRP3 inflammasome.
宿主来源:
Plant
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
676.668
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>97% (HPLC)
CAS号:
489-32-7
分子式:
C33H40O15
溶解度:
Soluble in DMSO (20mg/ml) or DMF (20mg/ml).
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