IL1 Receptor 2 antibody-多抗-深圳欣博盛生物科技有限公司

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IL1 Receptor 2 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX27748

规格：500μl

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IL1 Receptor 2 antibody

反应种属:

Human

宿主来源:

Rabbit

实验应用:

Immunoassay

靶标/特异性:

The antibody reacts specificly with Human IL-1 RII.

同种型:

IgG

克隆性:

Polyclonal

克隆号:

纯化方式:

IgG fraction

偶联:

Unconjugated

产品浓度:

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

The IL-1 system includes two agonists (IL-1a and IL-1b), converting enzymes, antagonists, two receptors (IL-1 RI and IL-1 RII) and the IL-1 receptor accessory protein. The IL-1 RII is part of the antagonistic IL-1 mechanism. It is also known as decoy receptor and is a non signaling molecule which functions by capturing IL-1 and preventing it from interacting with the signaling IL-1 RI. The decoy IL-1 RII can after binding to IL-1 also recruit the IL-1 receptor accessory protein and thus inhibit by co-receptor competition. Further a soluble form of IL-1 RII exists which is shed, a process in which matrix metalloproteases have been found to play a role, by various cells including monocytes, polymorphonuclear cells, B cells and fibroblasts.

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