IL12 B Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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IL12 B Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：96-554

规格：0.02 mg

目录价：￥6405.75

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IL12 B Recombinant Protein

别名:

IL12B, CLMF, CLMF2, NKSF, NKSF2, p40

实验应用:

表达系统:

HEK293 cells

保存温度:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

Tris with Glycine, Arginine and NaCl, pH7.5

产地:

美国

生产商:

Prosci

功能与背景:

Interleukin-12 (IL12) is also known as natural killer cell stimulatory factor (NKSF), cytotoxic lymphocyte maturation factor (CLMF) , is a heterodimeric cytokine encoded by two separate genes, IL-12A (p35) and IL-12B (p40). IL12 is naturally produced by dendritic cells, macrophages and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation. IL-12 is involved in the differentiation of naive T cells into Th0 cells and plays an important role in the activities of natural killer cells and T lymphocytes.IL-12 also has anti-angiogenic activity, which means it can block the formation of new blood vessels. Interleukin-12 subunit beta (IL12B) also known as NKSF2, CLMF2 and P40. Interleukin-12 subunit beta has been shown to interact with IL23. A large excess of monomeric IL12B is also secreted by the cells producing IL12, and exhibits no demonstrable biological activity. Overexpression of IL12B gene has been shown to be associated with the pathogenesis of multiple sclerosis. In addition, studies have revealed that the promoter polymorphism of this gene is implicated in the severity of atopic and non-atopic asthma in children.

纯度:

>95% as determined by SDS-PAGE.

Accession #:

AAH67499

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