| 货号:AG-CR1-3546-M010 | 规格:10 mg | 目录价:¥420 |
| 货号:AG-CR1-3546-M050 | 规格:50 mg | 目录价:¥1680 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Ipragliflozin
别名:
ASP1941
产品描述:
Ipragliflozin is an orally active, highly potent sodium glucose co-transporter 2 (SGLT-2) inhibitor (IC50 = 7.4nM), selective over SGLT-1, 3, 4, 5 and 6. SGLT-2 is one subtype of SGLTs found almost exclusively in the proximal tubules of nephronic components in kidneys, playing a key role in the re-uptake of glucose in the proximal tubule of the kidneys. Inhibition of SGLT-2 reduces blood glucose by blocking renal glucose reabsorption and thereby increasing urinary glucose excretion (UGE). Anti-diabetic and anti-obesity agent. Shown to improve glycemic control and reduce body weight, furthermore, lowering hypoglycemic risk and abdominal symptoms. SGLT-2 inhibitors are likely to improve beta-cell function and insulin sensitivity and restore glucose homeostasis. Attenuates non-alcoholic steatohepatitis (NASH) development.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
404.5
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98%
CAS号:
761423-87-4
分子式:
C21H21FO5S
溶解度:
Soluble in DMSO, DMF or ethanol (all 20mg/ml).
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