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折扣/货期| 货号：AG-CN2-0097-M001 | 规格：1 mg | 目录价：￥840 |
| 货号：AG-CN2-0097-M005 | 规格：5 mg | 目录价：￥3360 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
K-252c
别名:
Staurosporine aglycone; Staurosporinone; Antibiotic K252c; 6,7,12,13-Tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one
产品描述:
Indolocarbazole alkaloid antibiotic. [1]. Potent cell permeable reversible and ATP-competitive PKC (protein kinase C) inhibitor with 10-fold selectivity over PKA (protein kinase A) [1-5]. Anticancer compound. Cytotoxic againt various cancer cell lines [6, 9,11]. Apoptosis inducer [11]. Antiviral compound against GCV-sensitive and -resistant strains of human cytomegalovirus (HCMV) [7]. LACTB (beta-lactamase), malate dehydrogenase (MDH2, MDHC, MDH1B, ME1. ME2, ME3) and chymotrypsin inhibitor [8]. Inhibits mixed lineage kinase (MLK) [10].
宿主来源:
Isolated from Streptomyces longisporoflavus.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
311.4
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark. Stock solutions are stable for at least 3 months when stored at -20°C.
产地:
瑞士
纯度:
>97% (HPLC)
CAS号:
85753-43-1
分子式:
C20H13N3O
溶解度:
Soluble in DMSO or methanol. Insoluble in water.
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