深圳欣博盛生物科技有限公司 a1

KLF4-TAT Recombinant Protein
品牌:ProSci LLC
货号:40-524-0.005 mg 规格:0.005 mg 目录价:¥3783
货号:40-524-0.025 mg 规格:0.025 mg 目录价:¥5674.5
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
KLF4-TAT Recombinant Protein
别名:
EZF, GKLF, EZF, Krueppel-like factor 4, Epithelial zinc finger protein EZF
表达系统:
HEK293 cells
保存温度:
The lyophilized KLF4-TAT recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted KLF4-TAT is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing KLF4-TAT recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
KLF4 is a member of the Kruppel-like factor (KLF) family of zinc finger transcription factors. Members of this family have in common 3 contiguous C2H2-type zinc fingers at the carboxyl terminus that comprise the DNA-binding domain. KLF4 is highly expressed in skin and gut epithelial tissues, but is also found in various other cells and tissues, including vascular endothelial cells, lymphocytes, lung, and testis. It is an important regulator of the cell cycle, transcription, and cell differentiation. Together with Sox2, Oct4, and cMyc, KLF4 can induce the reprogramming of primary human fibroblasts to a pluripotent state. KLF4 and other transcription factors can be introduced into cells by DNA transfection, viral infection, or microinjection. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors into primary as well as transformed cells. Recombinant Human KLF4-TAT is a 483 amino acid protein, including a 13-residue C-terminal TAT peptide, with a calculated molecular weight of 51.7kDa. Recombinant Human KLF4-TAT is a mixture of the expected sequence beginning at Met1 and a truncated isoform beginning at Tyr54. Due to post-translational modifications, SDS-PAGE gel shows bands at approximately 72 and 66kDa, under reduced conditions.
纯度:
Greater than 90% by SDS-PAGE gel and HPLC analyses.
生物活性:
Endotoxin level is less than 0.1 ng per ug (1EU/μg).
Accession #:
NP_004226.3
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