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折扣/货期| 货号：32-228 | 规格：0.1 mL | 目录价：￥8687.25 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
KSHVORF45 Antibody [2D4A5]
别名:
Protein ORF45
反应种属:
Virus
宿主来源:
Mouse
实验应用:
ELISA,WB
同种型:
IgG1
克隆性:
Monoclonal
克隆号:
2D4A5
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
to KSHV ORF45 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
存储溶液:
Ascitic fluid containing 0.03% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. ORF45 protein encoded by an immediate-early gene in the KSHV genome is characterized as a phosphorylated protein, and it is localized in the cytoplasm of infected cells. Studies have shown that ORF45 Protein interacted with cellular IRF-7 and blocked virus-mediated phosphorylation and nuclear translocation of IRF-7. In consequence, ORF45 efficiently inhibited virus-induced production of type I IFN. Zhu et al (2003) reported that the ORF45 Protein was associated with purified virions.
Accession #:
F5HDE4
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