| 货号:GTX12037 | 规格:25μg | 目录价:¥5000 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
LEF1 antibody [3A12]
别名:
lymphoid enhancer binding factor 1 , LEF-1 , TCF10 , TCF1ALPHA , TCF7L3
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB
同种型:
IgG1
免疫原:
synthetic peptide corresponding to amino acids 236-242 (DTSMSRF) of human LEF-1.
克隆性:
Monoclonal
克隆号:
3A12
纯化方式:
Purified immunoglobulin
偶联:
Unconjugated
产品浓度:
~1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.08% Sodium azide.
生产商:
GeneTex
功能与背景:
Lymphoid enhancer factor, LEF1, is a transcription factor of the High Mobility Group of DNA binding proteins. It is one member of a family of four proteins referred to as LEF/TCF transcription factors (LEF1, TCF1, TCF3 and TCF4). These factors play crucial roles in WNT/Wingless signaling, a signal transduction cascade that directs cell differentiation. Aberrant activation of the WNT/Wingless pathway is also a root cause in the genesis of certain cancers such as colon cancer, melanoma and breast cancer.
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