官网链接
折扣/货期| 货号：AG-MR-C0047-M001 | 规格：1 mg | 目录价：￥1080 |
| 货号：AG-MR-C0047-M005 | 规格：5 mg | 目录价：￥3720 |
| 货号：AG-MR-C0047-M025 | 规格：25 mg | 目录价：￥11400 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Leucettinib-21
别名:
LCTB-21; (R,Z)-5-(Benzo[d]thiazol-6-ylmethylene)-2-((1-methoxy-4-methylpentan-2-yl)amino)-3,5-dihydro-4H-imidazol-4-one
产品描述:
Potent inhibitor of DYRK1A (IC50=2.4nM), DYRK1B (IC50=6.7nM), CLK1 (IC50=11.8nM) and CLK4 (IC50=5nM) kinases [2]. Inhibits the phosphorylation of Tau at Thr212 and cyclin D1 at Thr286, native DYRK1A in HT-22 cells and triggers cell apoptotic cell death. Corrects cognitive deficits in Ts65Dn model of Down syndrome and other models. iso-Leucettinib-21 (Prod. No. AG-MR-C0048) is a kinase-inactive isomer and should be used as a negative control together with this compound.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
358.5
产品形式:
solid
产地:
瑞士
纯度:
>99% (NMR)
CAS号:
2732859-75-3
分子式:
C18H22N4O2S
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询