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折扣/货期| 货号：AG-MR-C0049-M001 | 规格：1 mg | 目录价：￥960 |
| 货号：AG-MR-C0049-M005 | 规格：5 mg | 目录价：￥2520 |
| 货号：AG-MR-C0049-M025 | 规格：25 mg | 目录价：￥8400 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Leucettinib-92
别名:
LCTB-92; (Z)-2-((Adamantan-1-yl)amino)-5-(benzo[d]thiazol-6-ylmethylene)-3,5-dihydro-4H-imidazol-4-one
产品描述:
Potent inhibitor of DYRK1A (IC50=1.2nM), DYRK1B (IC50=1.8nM), DYRK3 (IC50=19.3nM) and CLK2 (IC50=0.6nM) [1]. Inhibits the phosphorylation of Tau at Thr212 and cyclin D1 at Thr286. Corrects cognitive deficits in animal models of Down syndrome. iso-Leucettinib-92 (Prod. No. AG-MR-C0050) is a kinase-inactive isomer and should be used as a negative control together with this compound.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
378.5
产品形式:
solid
产地:
瑞士
纯度:
>99% (NMR)
CAS号:
2732859-57-1
分子式:
C21H22N4OS
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