货号:AG-CR1-3584-M005 | 规格:5 mg | 目录价:¥360 |
货号:AG-CR1-3584-M025 | 规格:25 mg | 目录价:¥1080 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Loxoribine
别名:
7-Allyl-8-oxoguanosine; RWJ 21757
产品描述:
Guanosine analog derivatized at position N7 and C8 [1]. Very potent immunostimulatory compound that increases cytokine production [2-5]. Antitumor and antiviral activity compound [5, 6, 7, 12]. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7) [7-10]. Co-incubation with thymidine homopolymer oligodeoxynucleotides (ODN) redirected the stimulatory effect of loxoribine away from TLR7 toward TLR8 [11]. Induces autophagy and autophagy-induced cell death in Caco-2 cells [12]. Shows adjuvant activity to increase the effectiveness of vaccines [4].
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
339.3
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C. Stock solutions are stable for at least 3 months when stored at -20°C.
产地:
瑞士
纯度:
>97%
CAS号:
121288-39-9
分子式:
C13H17N5O6
溶解度:
Soluble in DMSO (30mg/ml) or water (10mg/ml).
促销活动
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