| 货号:CDX-L0303-M100 | 规格:100 mg | 目录价:¥2772 |
| 货号:CDX-L0303-M250 | 规格:250 mg | 目录价:¥5166 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
LY2835219
别名:
LY2835219 methanesulfonate; Abemaciclib methanesulfonate; Abemaciclib mesylate; Bemaciclib
产品描述:
LY2835219 is an orally-bioavailable dual inhibitor of cyclin-dependent kinase 4 (CDK4) and CDK6 (IC50s = 2 and 10 nM, respectively). Through this mechanism, it blocks phosphorylation of retinoblastoma protein, resulting in arrest of cell cycling in the G1 phase. LY2835219 has antitumor action against xenografts when used alone or in combination with other chemotherapeutic compounds.
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
602.7
产品形式:
solid
产地:
瑞士
纯度:
>99%
CAS号:
1231930-82-7
分子式:
C27H32F2N8 . CH4O3S
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